Cognigenics Leading Edge

SCIENCE

Evidence and Feasibility

Evidence

Hundreds of experiments show that calmer alpha and theta brainwave states are correlated with reduced stress and improved mental acuity, concentration and cognitive performance.  Dozens of experiments  demonstrate the efficacy of these states for helping specifically with Alzheimer’s.   

 

Over 20 additional experiments show conscious attention and cognitive capacity expand when brainwave activity is attenuated.  Although counterintuitive, this body of evidence clearly suggests an inverse relationship between brainwave activity and cognitive ability.

Feasibility

Over 30 published studies on CRISPR/Cas9 with adeno-associated viral (AAV) vectors have reported successful in vivo genome editing in mice.  CRISPR – AAV experiments at the Max Planck Florida Institute for Neuroscience and the University of Beijing have demonstrated precise editing in mature mouse neurons in vivo regardless of cell maturity, brain region or age.  The methods tested well in an aged Alzheimer’s disease mouse model even at advanced ages

Brainwaves

1. Beta State: (16 to 30 Hz)  Beta waves are associated with the alert mind state of the prefrontal cortex. This is a state of the “working” or "thinking mind": analytical, planning, assessing and categorizing, where we function for most of the day,  Excess beta is associated with stress.

2. Alpha State: (9 to 15 Hz)  In this state, our thinking and our brain waves start to slow down. We feel more calm, peaceful and grounded. We often find ourselves in an “alpha state” during a yoga class, spending time in Nature, or any activity that helps relax the body and mind. We are lucid, relaxed and reflective.

3. Theta State: (4 to 8 Hz)  Here the verbal thinking mind transitions to the meditative mind. We begin to move from the planning mind to a deeper state of consciousness, with stronger intuition, and greater capacity for clarity, visualization and problem-solving.

4. Delta State: (1 to 3 Hz) Tibetan monks who have been meditating for decades can reach this in an alert, wakened phase, but most of us experience this state during deep sleep.

5. Summary:  Alpha = relaxation (stress reduction).  Theta = attention (cognitive clarity)

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